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Synthetic biology “Design” alone is not enough to develop commercially viable strains

We go beyond the “Design” of microorganisms through synthetic biology, refining strain improvement technologies to develop microorganisms for commercial-scale production. 

How Can We Develop Strains for Real-World Production?

Synthetic biology “Design” is limited in scope and cannot precisely engineer the complex regulatory mechanisms of the entire strain. To cultivate a strain and produce a target product, it is necessary to address not only the metabolic pathways responsible for production, but also the complex regulation of gene expression and metabolic pathways arising from dynamic interactions between the cultivation environment and the intracellular state.

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CHITOSE’s Track Record in Developing Strains
for Commercial-Scale Production 

Expertise in Microorganisms for

Continuously Refining Our Strain Development Technologies

20

+ Years

100

Track Record in Strain Development

Track Record of Industry Collaboration

Across a wide range of strains and functional improvements

+ Projects

50

Across a wide range of industries, including food, pharmaceuticals, algae, agriculture, and environmental applications 

Track Record of Industry Collaboration

+ companies

Enhancing Production Yields, Optimizing Strain Characteristics, and More.

Beyond increasing production yields, we can modify cell viscosity and other strain characteristics to enhance production performance. Our strength lies in integrating genetic design, strain improvement, and cultivation process development.

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Chitose's strain-development technologies

01

Gene introduction and expression optimization

02

Breeding — disparity mutagenesis

03

TRACE-Based Enzyme improvement

04

Screening technology

SERVICE FLOW

Service Flow From consultation to delivery

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We work closely with you throughout the process to develop strains that better meet your specific requirements.

If desired, we also offer consultation on optimizing strain cultivation methods and conditions.

*Although our proprietary technologies have been shown to work across a wide range of organisms, we first evaluate its mutagenic effects for each new target before initiating strain improvement.

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